Prolactin
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This test is the primary test for the evaluation of galactorrhea (inappropriate lactation). Pituitary function test useful in the detection of prolactin secreting pituitary tumors (microadenomas, macroadenomas) with or without galactorrhea, with or without structural evidence of sellar enlargement. An adult female premenopausal patient having amenorrhea(no menses) and galactorrhea is highly suspect of pituitary prolactinoma and is a candidate for radiologic evaluation of the pituitary as well as serum prolactin levels.
Elevated prolactin may be associated with corpus luteum insufficiency or anovulation. The associated results of hyperprolactinemia include amenorrhea(no menses), anovulation, and decreased bone density. Normal prolactin level does not rule out pituitary tumor. Prolactin secretion is episodic and is influenced
by stress and by low glucose levels.
Elevated prolactin may be associated with corpus luteum insufficiency or anovulation. The associated results of hyperprolactinemia include amenorrhea(no menses), anovulation, and decreased bone density. Normal prolactin level does not rule out pituitary tumor. Prolactin secretion is episodic and is influenced
by stress and by low glucose levels.